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Reading Map: The Immortal Life of Henrietta Lacks

Fiction

Positive Match
Tony Chiu

How does the organ donor transport firm MedEx come up with so many needed body parts so quickly, and at such good prices? Dr. Nguyen-Anh Dupree, a Vietnamese American physician working in Mexico for the charitable group Doctors Without Borders, stumbles on the nasty answer: MedEx is also in the business of transporting illegal aliens. And then there's the link between MedEx and the giant health care firm Caduceus 21 that is about to launch a huge stock offering.

The Passage
Justin Cronin

This epic is about a virus that nearly destroys the world, and a six-year-old girl who holds the key to bringing it back. The Passage takes readers on a journey from the early days of the virus to the aftermath of the destruction, where packs of hungry infected scour the razed, charred cities looking for food, and the survivors eke out a bleak, brutal existence shadowed by fear. Cronin doesn't shy away from identifying his "virals" as vampires. These are a creation all Cronin's own--hairless, insectile, glow-in-the-dark mutations who are inextricably linked to their makers and the one girl who could destroy them all.

Dead End
Brian Freemantle

British scientist Richard Parnellis recruited to work for leading American pharmaceutical firm Dubette. When he arrives on the job, eager to set up his own cutting-edge pharmacogenomics department, he learns that, far from being open and friendly as he was led to expect, the Dubette workplace is rigidly controlled and secretive. Commiserating with colleague Rebecca Lang leads to romance and the possibility of marriage, but Rebecca is extremely concerned about a missing drug shipment from France. Then she's killed in a car crash, and Richard is accused of running her off the road after a lover's quarrel. Richard soon realizes that Rebecca's death was no accident and that his own life may be in danger, especially when he discovers that a potentially lethal drug sample from Dubette's French subsidiary has been released in Africa.

The Constant Gardener
John Le Carré

British diplomat Justin Quayle, complacent raiser of freesias and doting husband of the stunning, much younger Tessa, has tended his own garden in Nairobi too long. Tessa is Justin's opposite, a fiery reformer, "that rarest thing, a lawyer who believes in justice," whose campaigns have earned her a nickname: "the Princess Diana of the African poor." But now Tessa has turned up naked, raped, and dead on a mysterious visit to remote Lake Turkana in Kenya. Her traveling companion (and lover?), the handsome Congolese-Belgian doctor Arnold Bluhm, has vanished. So has Quayle's complacency. Tessa had been compiling data against a multinational drug company that uses helpless Africans as guinea pigs to test a tuberculosis remedy with unfortunately fatal side effects. Her report was destroyed by her husband's superiors; was she? The home office tries to take Quayle in out of the cold. He cleverly eludes their clammy embrace, turns spy, and takes off on a global chase to avenge Tessa and solve her murder.

Blood Double
Neil McMahon

Carroll Monks is the crime solving emergency-room doctor in this fast-paced intelligent medical thriller. When a man who calls himself John Smith turns up in the ER, and he just happens to bear a striking resemblance to a filthy rich computer genius, Monks suspects somebody's not telling him the whole story. When the computer genius turns up missing, and somebody waltzes into Monks' hospital and steals the blood samples taken from Smith, our hero smells a conspiracy. Monks combines his medical expertise with his knack for detection to filter out the lies and false leads and get to the truth.

Medical Experiments

Undue Risk : Secret State Experiments on Humans
Jonathan D. Moreno
174.28 MOR
Between 1949 and 1969, the U.S. Army conducted over 200 "field tests" as part of its biological warfare research program, releasing infectious bacterial agents in cities across the U.S. without informing residents of the exposed areas, Moreno reveals in this chilling, meticulously documented casebook. A professor of biomedical ethics at the University of Virginia, Moreno (Arguing Euthanasia) served on a Clinton-appointed advisory committee that blew the lid off the government's secret radiation experiments from WWII through the mid-1970s, which involved the injection of unwitting human volunteers with plutonium, uranium and other radioactive substances. Moreno's survey extends from Walter Reed's turn-of-the-century yellow fever research to the infamous Tuskegee syphilis study; from army and air force mind control experiments (1950—1975) involving ingestion of LSD and incapacitating chemicals by thousands of subjects, often without their consent, to the compulsory vaccination of Gulf War Gis with botulism toxin vaccine not approved by the FDA that may have contributed to "Gulf war syndrome.

Medical Apartheid : the Dark History of Medical Experimentation on Black Americans from Colonial Times to the Present
Harriet A. Washington
174.28WAS
The shameful history of the physical and medical misuse of African Americans began long before the infamous Tuskegee experiment of the 1930s. Washington, a medical journalist, offers the first and only comprehensive history of medical experimentation on and mistreatment of black Americans. Starting with the racist pseudoscience that began when whites first encountered Africans, Washington traces practices from grave robbing to public display of black albinos and the "Hottentot Venus," and theories from eugenics to social Darwinism, which have attempted to justify views of racial hierarchy and mistreatment and even enslavement of blacks. Washington draws on medical journals and previously unpublished reports that openly acknowledged racial attitudes and experimentation, protected by the fact that the public and the media rarely read or understood such reports and often shared similar feelings on the subject. Washington also details a litany of medical abuses and experimentation aimed at black men in the military and in prison, as well as women and children, all without proper notification or consent.

Human Medical Trials
Kelly Barth, book editor
610.72 HUM
Two medical trials came to light in the 1970s that caused the United States medical community to reexamine the way humans are used in such experiments. The Tuskegee Syphilis Study and the hepatitis study at the Willowbrook School fueled controversy within the medical and political community, raising questions that must still be considered today.

The Plutonium Files : America's Secret Medical Experiments in the Cold War
Eileen Welsome
616.9897WEL
As World War II reached its climax, the U.S. push to create an atomic bomb spawned an industry the size of General Motors almost overnight. But a little-understood human dilemma quickly arose: How was all the radiation involved in building and testing the bomb going to affect the countless researchers, soldiers, and civilians exposed to it? Government scientists scrambled to find out, fearing cancer outbreaks and worse, but in their urgency conducted classified experiments that bordered on the horrific: MIT researchers fed radioactive oatmeal to residents of a state boys' school outside Boston; prisoners in Washington and Oregon were subjected to crippling blasts of direct radiation; and patients with terminal illnesses (or so it was hoped) were secretly injected with large doses of plutonium—survivors were surreptitiously monitored for years afterward.

In the Name of Science : a History of Secret Programs, Medical Research, and Human Experimentation
Andrew Goliszek
619.98GOL
People throughout history have used their fellow human beings for experimentation, most often in the name of military or financial domination. The author, a biology professor at North Carolina A & T State University, says unprecedented medical advances such as the Human Genome Project have put us on the brink of discoveries "that will make real the threat of population control, gene warfare, ethnic cleansing, or worse." The best way to ensure that the past is not repeated, Goliszek argues, is to document the truth about it in all its chilling detail, which he effectively accomplishes here. The book is a compendium of damning evidence that implicates first and foremost our own government, our doctors and corporations, and ultimately ourselves. The book features copious primary documentation, but it doesn't read like an evidentiary record. He introduces readers to the terrifying but intriguing shadow worlds of chemical and biological engineering; CIA mind-control experiments; the American eugenics movement of the past and present; and ethnic weaponry tailored to the genetic specifications of the targeted race. A recurrent theme here is how often experimentation involves subjects who have not consented. The most unsettling chapter gives firsthand accounts by victims of Cold War CIA experiments on children: brainwashing and mind control using chemicals, radiation, hypnosis, electric shock, isolation and physical torture, all reportedly to create the perfect spy-assassin.

Bioethics

First, Do No Harm : a Summer of Life and Death Decisions at a Texas Hospital
Lisa Belkin
174.2BEL
Taking her title from the physicians' Hippocratic Oath, Belkin, spent nearly three years with the Hermann Hospital Ethics Committee in Houston, Texas, researching this book on medical ethics. The daily, convulsive questions of life and death that the committee struggles with are often questions without answers, yet they are somehow answered at the Hermann Hospital and in hospitals across the country every single day. Belkin quotes a Chinese proverb: if you save a life, you are responsible for it. The cruel, deceptively simple wisdom of this proverb is brought home on nearly every page of this entirely true, gripping, and dramatic account of how medical chance and technology trap the unsuspecting in a vise of brutal decision-making.

The Ethics of Organ Transplants: the Current Debate
Arthur Caplan
174.25ETH
Renowned bioethicist Caplan (Ctr. For Bioethics, Univ. of Pennsylvania) and medical writer Coelho have selected 35 articles that are representative of the ethical issues surrounding organ transplantation. Scarcity of organs and the high costs involved in these procedures force difficult legal, philosophical, scientific, and economic choices. What are the sources of organs used in transplantation? How can we make the procurement system more efficient? Should we pay for organs? Should someone who has already received one transplant be allowed a second? Should alcoholics be given liver transplants? Are transplants really worth the tremendous costs? These are just a few of the questions discussed here.

Future Bioethics: Overcoming Taboos, Myths, and Dogmas
Ronald Lindsay
174.957LIN
From discussions about abortion to end of life, bioethicists are there. Ronald Lindsay, a lawyer with a doctorate in bioethics, is particularly well placed to bring his voice to the arena in this book. Discussions often begin from controversial positions that are entrenched in dogma. Lindsay's mission is to expose and debunk these myths. Each chapter is informed by factual and theoretical discussion and approached in the common-sense way that Lindsay recommends. His use of practical examples to point out inconsistencies in arguments is vivid and gives the non-expert reader insight into these issues.

The Body Hunters : Testing New Drugs on the World's Poorest Patients
Sonia Shah
362.1782SHA
Hailed by John le Carré as "an act of courage on the part of its author" and singled out for praise by the leading medical journals in the United States and the United Kingdom, The Body Hunters uncovers the real-life story behind le Carré's acclaimed novel The Constant Gardener and the feature film based on it. Drawing on years of original research and reporting in Africa and Asia, Shah examines how the multinational pharmaceutical industry, in its quest to develop lucrative drugs, has begun exporting its clinical research trials to the developing world, where ethical oversight is minimal and desperate patients abound. As the New England Journal of Medicine notes, "it is critical that those engaged in drug development, clinical research and its oversight, research ethics, and policy know about these stories," which tell of an impossible choice being faced by many of the world's poorest patients—be experimented upon or die for lack of medicine.

Strangers at the Bedside : a History of How Law and Bioethics Transformed Medical Decision Making
David J. Rothman
610.72ROT
Rothman, a bioethicist at Columbia University, traces the dramatic and profound changes that have taken medical decision-making out of the hands of physicians in the past half-century. His historical analysis, which covers medical research and human experimentation in the United States with a focus on the post-World War II era, is highly informative. This is not a case-by-case study as many bioethics books are, but rather an informed interpretation of why there are so many ethics cases in contemporary medicine to consider.

Cadavers & Body Parts

The Nicholas Effect : a Boy's Gift to the World
Reg Green
362.1783 GRE
As his vacationing family drove through southern Italy on a summer night in 1994, seven-year-old Nicholas Green, asleep in the back seat, was shot in the head during a botched robbery. The next day his parents made what was for them the "least major decision either of us has ever had to make": to donate Nicholas's organs. What was for them almost an afterthought in their shock and grief had an electrifying effect on Italy and the world. Organ donations were uncommon in Italy prior to Nicholas's death; donor card signings surged afterwards. The Greens' generosity was greeted with an outpouring of sympathy, admiration, and a profound change in the attitude toward organ donation.

Black Markets : the Supply and Demand of Body Parts
Michele Goodwin
362.19GOO
Goodwin exposes the fraud, bias, and commercialism that exists in our supposedly altruistic system of organ donation. The needs and views of African Americans are at the center of this work. lt will cause readers to rethink not only organ donation but the nature of altruism itself.

Donor: How One Girl's Death Gave Life to Others
John Pekkanen
362.795PEK
Medical journalist Pekkanen follows the donation of organs from a young women after her death in an automobile accident. The reader follows the work of Jo Leslie and her staff at the Maryland Organ Procurement Center as they race against time to place two kidneys and two corneas in patients in Maryland, Massachusetts, and Ohio. It is a fascinating story that highlights the anguish and drama of organ donation. The reader gains an understanding of the emotions felt by the families, as well as insight into the politics and barriers faced in organ procurement.

Body of Work : Meditations on Mortality from the Human Anatomy Lab
Christine Montross
611MON
"You begin to learn to heal the living by dismantling the dead," says Montross, and though her recollections encompass all of her medical training, the narrative backbone of the story is her semester-long dissection of a human cadaver, from opening up the ribcage to removing the brain from the skull. Performing her own dissection leads Montross to explore the history of studying anatomy through corpses, which brings tantalizing detours to medieval Italian universities and saints' shrines. But she also recounts her earliest encounters with living patients, such as a heart-wrenching consultation with a man suffering from Lou Gehrig's disease, who can communicate only by blinking.

Stiff : the Curious Lives of Human Cadavers
Mary Roach
611ROA and BO-CD 611ROA
Roach has written a book as informative and respectful as it is irreverent and witty. From her opening lines ("The way I see it, being dead is not terribly far off from being on a cruise ship. Most of your time is spent lying on your back"), it is clear that she's taking a unique approach to issues surrounding death. Roach delves into the many productive uses to which cadavers have been put, from medical experimentation to applications in transportation safety research (in a chapter archly called "Dead Man Driving") to work by forensic scientists quantifying rates of decay under a wide array of bizarre circumstances. There are also chapters on cannibalism, including an aside on dumplings allegedly filled with human remains from a Chinese crematorium, methods of disposal (burial, cremation, composting) and "beating-heart" cadavers used in organ transplants.

Other Reading Maps:
Animal, Vegetable, Miracle : A Year of Food Life
Freedom
Island Beneath the Sea
The Last Stand: Custer, Sitting Bull, and the Battle of the Little Bighorn
More Than It Hurts You
Murder in Greenwich: Who Killed Martha Moxley?
Room: a Novel